Saliva sample testing is a robust and reliable non-invasive alternative to the NP swab method for SARS-CoV-2 RNA detection, as well as a promising tool for COVID-19 screening.
Infect Drug Resist. 2021 Jul 27;14:2943-2951.
"in this study, we analyzed two patients whose ALK statuses
were not consistent using these four methods. We explored the potential reasons for deviation of the test results and found a novel EML4-ALK break site, which had been not described previously."
Thorac Cancer. 2021 Sep 6.
we propose a palindromic-assisted self-annealing transcription amplification (PASTA) strategy for the reliable detection of circulating EGFR exon mutations.
Biosens Bioelectron. 2021 Dec 15;194:113633.
This model was able to give an accurate prediction of LCNEC and SCLC. It may assist clinicians to make the optimal decision for patients with pulmonary neuroendocrine tumors in choosing appropriate treatment.
Transl Oncol. 2021 Sep 14;14(12):101222.
"Our study found that MET genomic alterations were statistically related to age and tumor stage and co-existed with mutations of other oncogenic driver genes, such as EGFR and BRAF. Moreover, various splicing site changes at the DNA level led to the
exon 14 skipping mutation at the mRNA level. Further studies are required to clarify the association between MET genomic alterations and prognosis."
Front Oncol. 2021 Sep 30;11:755031.
LUAD patients with concomitant PTB have a poor response to EGFR-TKI treatment, especially in terms of survival outcome.
Cancer Manag Res. 2021 Oct 1;13:7517-7526.